Probably Jake Gyllenhaal and Josh Groban would assure a good limited sell out run.
It would *have* to be a limited run, IMO, to get 2 stars for the brothers - Dr. Craven is really a rather minor role, aside from "Lily's Eyes." (Unless they did a Topdog/Underdog kind of thing and have them switch roles during the run, lol. But that seems silly.)
True that Westenberg was well-known in the theatre community by the time he did the role - and certainly he had solid credits, etc. But he wasn't a real "star" - certainly not the way Patinkin was. I think that's who you ideally want in the role - someone who may be a favorite among theatre people, but not a huge star type. Keep in mind that the video of Into The Woods was first shown on PBS just a month before the run of The Secret Garden started.)